Like most mood disorders, atypical depression is believed to be caused by a mix of:
- Genetic vulnerability.
- Neurochemical imbalances (serotonin, dopamine, norepinephrine).
- Hormonal dysfunction (especially the HPA axis).
- Environmental factors like childhood trauma, chronic stress, or interpersonal issues.
One notable theory is that people with atypical depression may have blunted dopamine activity, which could explain the excessive sleep, increased appetite (particularly for carbs), and mood reactivity.
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